Differential effect of platelet-rich plasma fractions on β1-integrin signaling, collagen biosynthesis, and prolidase activity in human skin fibroblasts

Abstract

The study was conducted to evaluate the effects of platelet-rich plasma (PRP), supernatant of PRP (SPRP) obtained by centrifugation, and supernatant of activated PRP (SActi-PRP) obtained by Ca2+ solution-treated PRP on collagen biosynthesis, prolidase activity, and β1-integrin signaling in cultured human skin fibroblasts. Incubation of fibroblasts with 5… (More)
DOI: 10.2147/DDDT.S135949

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@inproceedings{Guszczyn2017DifferentialEO, title={Differential effect of platelet-rich plasma fractions on β1-integrin signaling, collagen biosynthesis, and prolidase activity in human skin fibroblasts}, author={Tomasz Guszczyn and Arkadiusz Surażyński and Ilona Zaręba and Edyta Rysiak and Janusz Popko and Jerzy A. Pałka}, booktitle={Drug design, development and therapy}, year={2017} }