Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson’s Disease

@inproceedings{Kumar2015DifferentialEO,
  title={Differential effect of caffeine intake in subjects with genetic susceptibility to Parkinson’s Disease},
  author={Prakash M. Kumar and Swe Swe Thet Paing and Hui Li and Ratnagopal Pavanni and Yih Yuen and Yun Zhao and Eng-King Tan},
  booktitle={Scientific reports},
  year={2015}
}
We examined if caffeine intake has a differential effect in subjects with high and low genetic susceptibility to Parkinson's disease (PD), a common neurodegenerative disorder. A case control study involving 812 subjects consisting of PD and healthy controls were conducted. Caffeine intake assessed by a validated questionnaire and genotyping of PD gene risk variant (LRRK2 R1628P) was carried out. Compared to caffeine takers with the wild-type genotype (low genetic susceptibility), non-caffeine… CONTINUE READING
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The authors declare no competing financial interests

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