Differential effect of TEA on long-term synaptic modification in hippocampal CA1 and dentate gyrus in vitro.

@article{Song2001DifferentialEO,
  title={Differential effect of TEA on long-term synaptic modification in hippocampal CA1 and dentate gyrus in vitro.},
  author={Dong Song and Xinmin Xie and Zhihua Wang and Theodore W Berger},
  journal={Neurobiology of learning and memory},
  year={2001},
  volume={76 3},
  pages={375-87}
}
The effectiveness of tetraethylammonium (TEA) and high-frequency stimulation (HFS) in inducing long-term synaptic modification is compared in CA1 and dentate gyrus (DG) in vitro. High-frequency stimulation induces long-term potentiation (LTP) at synapses of both perforant path-DG granule cell and Schaffer collateral-CA1 pyramidal cell pathways. By contrast, TEA (25 mM) induces long-term depression in DG while inducing LTP in CA1. The mechanisms underlying the differential effect of TEA in CA1… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 23 references

Similar Papers

Loading similar papers…