Differential dynamics of splicing factor SC35 during the cell cycle

Abstract

Pre-mRNA splicing factors are enriched in nuclear domains termed interchromatin granule clusters or nuclear speckles. During mitosis, nuclear speckles are disassembled by metaphase and reassembled in telophase in structures termed mitotic interchromatin granules (MIGs). We analysed the dynamics of the splicing factor SC35 in interphase and mitotic cells. In… (More)
DOI: 10.1007/s12038-008-0054-3

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