Differential down-regulation of estrogen receptor-like immunoreactivity by estradiol in the female Brazilian opossum brain.

@article{Pearson1993DifferentialDO,
  title={Differential down-regulation of estrogen receptor-like immunoreactivity by estradiol in the female Brazilian opossum brain.},
  author={Paul L. Pearson and L. R. Ross and Carol D. Jacobson},
  journal={Brain research},
  year={1993},
  volume={617 1},
  pages={171-5}
}
The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovariectomized controls. These results support a down-regulatory role for estrogen in relation to its receptor in the brain, and indicate that ER-LI is differentially regulated in the… CONTINUE READING
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