Differential dopaminergic regulation of the neurotensin striatonigral and striatopallidal pathways in the rat.

@article{Castel1994DifferentialDR,
  title={Differential dopaminergic regulation of the neurotensin striatonigral and striatopallidal pathways in the rat.},
  author={M N Castel and Patrizia Morino and Ingrid Nylander and Lars Terenius and Tomas G M H{\"o}kfelt},
  journal={European journal of pharmacology},
  year={1994},
  volume={262 1-2},
  pages={1-10}
}
Recently the existence of a neurotensin striatonigral pathway strongly up-regulated by methamphetamine has been demonstrated. The aim of the present study was to investigate, using immunohistochemistry and radioimmunoassay, the modulation of this pathway by dopamine antagonists. Rats were injected either with methamphetamine alone or together with the dopamine D1 receptor antagonist, SCH 23390 (R(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-be nzapine hydrochloride), or with… CONTINUE READING

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