Differential distribution of glycine transporters in Müller cells and neurons in amphibian retinas

  title={Differential distribution of glycine transporters in M{\"u}ller cells and neurons in amphibian retinas},
  author={Zheng Jiang and Baoqin Li and Frantisek Jursky and Wen Shen},
  journal={Visual Neuroscience},
  pages={157 - 168}
Amphibian retinas are commonly used for electrophysiological studies on neural function and transduction because they share the same general properties as higher vertebrate retinas. Glycinergic synapses have been well described in amphibian retinas. However, the role of glycine transporters in the synapses is largely unknown. We studied the distribution and function of glycine transporters in the retinas from tiger salamanders, mudpuppies, and leopard frogs by immunofluorescence labeling and… 
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Glycine input induces the synaptic facilitation in salamander rod photoreceptors.
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Glycine transporters (glycine transporter 1 and glycine transporter 2) are expressed in retina
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Glycine transporter 1 modulates GABA release from amacrine cells by controlling occupancy of coagonist binding site of NMDA receptors.
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University of Minnesota Ph.D. dissertation. Major: Neuroscience. Advisor: Robert F. Miller, MD. 1 computer file (PDF); v, 130 pages. Ill. (some col.)


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The results indicate the presence of different glycine transporter isoforms in the frog retina, acting mainly through the classical inhibitory glycine system.
Distribution of the glycine transporter glyt-1 in mammalian and nonmammalian retinae.
In monkeys, cats, and rats, populations of cells which the authors interpret as being glycine-containing interplexiform cells expressed glyt-1: these cells lacked a content of glutamate, suggesting they are not bipolar cells.
Expression of glycine and the glycine transporter Glyt-1 in the developing rat retina
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Excitatory Amino Acid Transporters of the Salamander Retina: Identification, Localization, and Function
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Immunocytochemical localization of glycine and glycine receptors in the retina of the frog Rana ridibunda
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Localization of the GLYT1 glycine transporter at glutamatergic synapses in the rat brain.
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