Differential distribution of endothelin peptides and receptors in human adrenal gland

@article{Davenport1996DifferentialDO,
  title={Differential distribution of endothelin peptides and receptors in human adrenal gland},
  author={Anthony P. Davenport and Sherria L. Hoskins and Rhoda E. Kuc and Christopher Plumpton},
  journal={The Histochemical Journal},
  year={1996},
  volume={28},
  pages={779-789}
}
Sub-type selective ligands revealed a differential distribution of endothelin (ET) receptors within human adrenal glands. High densities of ETA receptors were localized, using [125I]-PD151242, to the smooth muscle layer of the arteries, smaller vessels within the capsular plexus and to the secretory cells of zona glomerulosa (K D=139.8±39.7,B max=69.7±9.1 fmol mg−1 protein, mean of 3 individuals±sem). ETB receptors were present in the medulla (K D=145.2±16.4,B max=75.5±12.3), zona glomerulosa… CONTINUE READING
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