Differential distribution of annexins-I, -II, -IV, and -VI in synovium.

  title={Differential distribution of annexins-I, -II, -IV, and -VI in synovium.},
  author={Nicolas J. Goulding and Josh J Dixey and Eric F Morand and Ricardo A. Dodds and L. S. Wilkinson and Andrew A. Pitsillides and J C W Edwards},
  journal={Annals of the rheumatic diseases},
  volume={54 10},
OBJECTIVES To examine the distribution of four annexins in non-inflamed rheumatoid arthritic and osteoarthritic synovial tissue. METHODS Frozen sections were stained with monoclonal antibodies (MAb) specific for annexins-I, -II, -IV, and -VI, and for cell lineage related markers including CD68 and CD14 (macrophages), prolyl hydroxylase (fibroblasts), and CD3 (T cells). RESULTS Each of the annexins was present in synovial tissues in significant amounts in the three groups studied. Annexin-I… CONTINUE READING