Differential diagnosis of pleural effusions by fuzzy-logic-based analysis of cytokines.

  title={Differential diagnosis of pleural effusions by fuzzy-logic-based analysis of cytokines.},
  author={Pawel Chomej and Katrin Bauer and N. Bitterlich and David S. C. Hui and Kin Sang Chan and Helga Gosse and Joachim Schauer and Gerhard Hoheisel and Ulrich Sack},
  journal={Respiratory medicine},
  volume={98 4},
Pleural effusions can be caused by highly different underlying diseases and are characterized by complex interactions of various local and circulating cells as well as numerous soluble parameters like interleukins (IL). Knowledge about this complex network could help to indicate underlying disease. Therefore, we have investigated immunoreactive concentrations of IL-4, IL-6, IL-11, IL-15, IL-17, IL-18, and tumor necrosis factor-alpha (TNF-alpha) in pleural effusions and peripheral blood from… CONTINUE READING


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