Differential diagnosis in chronic lymphocytic leukaemia.

@article{Matutes2007DifferentialDI,
  title={Differential diagnosis in chronic lymphocytic leukaemia.},
  author={Estella Matutes and Andrew Charles Wotherspoon and Daniel Catovsky},
  journal={Best practice & research. Clinical haematology},
  year={2007},
  volume={20 3},
  pages={367-84}
}
The diagnosis of chronic lymphocytic leukaemia (CLL) is based on clinical and laboratory features. Morphology and immunophenotype are the key initial diagnostic tests. In cases with atypical features, these investigations should be complemented with cytogenetics and/or histology to confirm the diagnosis and to exclude other B-cell disorders. Morphologically, CLL can be classified into typical and atypical forms. Cell-marker studies provide a robust foundation to establish the diagnosis as the… CONTINUE READING

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