Differential diagnosis for bilateral abnormalities of the basal ganglia and thalamus.

@article{Hegde2011DifferentialDF,
  title={Differential diagnosis for bilateral abnormalities of the basal ganglia and thalamus.},
  author={Amogh Narayan Hegde and Suyash Mohan and Narayan Lath and Choie Cheio Tchoyoson Lim},
  journal={Radiographics : a review publication of the Radiological Society of North America, Inc},
  year={2011},
  volume={31 1},
  pages={
          5-30
        }
}
  • A. Hegde, S. Mohan, +1 author C. T. Lim
  • Published 19 January 2011
  • Medicine
  • Radiographics : a review publication of the Radiological Society of North America, Inc
The basal ganglia and thalamus are paired deep gray matter structures that may be involved by a wide variety of disease entities. The basal ganglia are highly metabolically active and are symmetrically affected in toxic poisoning, metabolic abnormalities, and neurodegeneration with brain iron accumulation. Both the basal ganglia and thalamus may be affected by other systemic or metabolic disease, degenerative disease, and vascular conditions. Focal flavivirus infections, toxoplasmosis, and… Expand
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References

SHOWING 1-10 OF 88 REFERENCES
Magnetic resonance imaging findings in bilateral basal ganglia lesions.
  • C. Lim
  • Medicine
  • Annals of the Academy of Medicine, Singapore
  • 2009
TLDR
Careful assessment of radiological findings outside the basal ganglia, such as involvement of the cortex, white matter, thalamus and pons, together with clinical correlation, may be helpful in narrowing the differential diagnosis, and directing further radiological, biochemical or genetic investigations. Expand
MRI demonstration and CT correlation of the brain in patients with idiopathic intracerebral calcification
TLDR
The hyperintense T2 signals may reflect a slowly progressive, metabolic or inflammatory process in the brain which subsequently calcifies and are probably responsible for the neurological deficit observed. Expand
Diagnostic Approach in Patients with Symmetric Imaging Lesions of the Deep Gray Nuclei
TLDR
While presentations may vary in individual patients, the essentials of history, clinical examination, laboratory evaluation, and neuroimaging lesion pattern can be efficiently directed to differentiate the various etiologies of deep gray matter nuclei lesions. Expand
Early CT findings of global central nervous system hypoperfusion.
TLDR
The abnormal CT findings can be ascribed to increased vulnerability of the cerebral cortex and basal ganglia to hypotensive episodes, due to the large metabolic demand of these regions and their characteristic local cerebral blood flow. Expand
Bilateral thalamic glioma: review of eight cases with personality change and mental deterioration.
TLDR
Bilateral glioma of the dorsomedial and intralaminar nuclei of the thalamus can be a primary cause of dementia that has not been well-recognized in the past and should be considered for patients presenting with personality change or dementia. Expand
Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: Clinical and neuropathological findings in 27 patients
TLDR
Clinical, neuroradiological, and serological findings in 27 patients with cerebral toxoplasmosis complicating the acquired immune deficiency syndrome, and double‐dose contrast administration and preliminary experience with magnetic resonance imaging suggested that these techniques were superior to standard CT scanning in detecting Toxoplasma lesions. Expand
Paramedian thalamic and midbrain infarcts: Clinical and neuropathological study
TLDR
The clinical and neuropathological findings in 28 cases of paramedian thalamic and midbrain infarcts are reported and marked disturbances of consciousness and behavior associated with ocular motility changes are observed. Expand
Thalamic involvement in sporadic Creutzfeldt-Jakob disease: a diffusion-weighted MR imaging study.
TLDR
A quantitative analysis of DW images with ADC measurements shows slight MR imaging changes in the thalamus in sCJD when abnormal SI may not be present. Expand
Brain lesions in patients with AIDS: H-1 MR spectroscopy.
TLDR
H-1 MR spectroscopic findings showed significantly different biochemical profiles for each diagnostic group with regard to N-acetyl compounds, total creatine pool, choline-containing compounds, myoinositol, and lactate. Expand
[Study of diffusion weighted magnetic resonance imaging in Wilson's disease].
TLDR
It is confirmed that diffusion MRI was very useful for estimating parenchymal lesions with metal deposits, especially in patients with Wilson's disease. Expand
...
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3
4
5
...