Differential cumene hydroperoxide sensitivity of cytochrome P-450 enzymes IA1 and IIB1 determined by their way of membrane incorporation.

@article{Balvers1992DifferentialCH,
  title={Differential cumene hydroperoxide sensitivity of cytochrome P-450 enzymes IA1 and IIB1 determined by their way of membrane incorporation.},
  author={W G Balvers and Marelle G. Boersma and Cees Veeger and Ivonne M C M Rietjens},
  journal={Biochimica et biophysica acta},
  year={1992},
  volume={1117 2},
  pages={179-87}
}
The cytochrome P-450-dependent O-dealkylation of alkoxyresorufins was used to study the effect of cumene hydroperoxide on cytochrome P-450 IIB1 and IA1 in microsomal and reconstituted systems. In liver microsomal systems from respectively phenobarbital and 3-methylcholanthrene pretreated male Wistar rats, cytochrome P-450 IIB1-dependent pentoxyresorufin-O… CONTINUE READING