Differential contributions of theobromine and caffeine on mood, psychomotor performance and blood pressure

@article{Mitchell2011DifferentialCO,
  title={Differential contributions of theobromine and caffeine on mood, psychomotor performance and blood pressure},
  author={Ellen Siobhan Mitchell and Marieke Slettenaar and Nosheen Meer and Catherine Transler and Linda A.W. Jans and Frits Quadt and Michael W. Berry},
  journal={Physiology \& Behavior},
  year={2011},
  volume={104},
  pages={816-822}
}
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92 Citations
Highly Influential Citations
3
Background Citations
40
Methods Citations
1
Results Citations
7

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92 Citations

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Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies.
TLDR
A substantial interaction between cocoa flavanols and methylXanthines exists at the level of absorption, in which the methylxanthines mediate an increased plasma concentration of (-)-epicatechin metabolites that coincides with enhanced vascular effects commonly ascribed to cocoa flavanol intake.
Acute effects of brewed cocoa consumption on attention, motivation to perform cognitive work and feelings of anxiety, energy and fatigue: a randomized, placebo-controlled crossover experiment
TLDR
Brewed cocoa can acutely reduce errors associated with attention in the absence of changes in either perceived motivation to perform cognitive tasks or feelings of energy and fatigue, and Supplemental caffeine in brewed cocoa can enhance aspects of attention.
The relevance of theobromine for the beneficial effects of cocoa consumption
TLDR
Theobromine, which is found in higher amounts than caffeine, seems to be behind several effects attributed to cocoa intake, and deserves attention as one of the most attractive molecules in cocoa.
Behavioural effects of compounds co-consumed in dietary forms of caffeinated plants
TLDR
It is highlighted that more research aimed at understanding the effects of these compounds is needed and, more importantly, the synergistic relationship that they may have with caffeine.
Acute hematological and mood perception effects of bitter orange extract (p‐synephrine) consumed alone and in combination with caffeine: A placebo‐controlled, double‐blind study
TLDR
Data indicate that consumption of 103‐mg p‐synephrine does not negatively impact acute blood parameters, does not augment the effects of caffeine, or produce stimulant‐like perceptual mood effects.
Mood Components in Cocoa and Chocolate: The Mood Pyramid.
TLDR
It is concluded that the mood and cognition-enhancing effects of cocoa and chocolate can be ranked from more general activities associated with flavanols and methylxanthines, to more specific activities related to minor constituents such as salsolinol, with on top the orosensory properties of chocolate.
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