Differential contribution of microglia and monocytes in neurodegenerative diseases

Abstract

Neuroinflammation is a hallmark of neurodegenerative diseases including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS). Microglia, the innate immune cells of the CNS, are the first to react to pathological insults. However, multiple studies have also demonstrated an involvement of peripheral monocytes in several… (More)
DOI: 10.1007/s00702-017-1795-7

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