Differential contribution of HP1 proteins to DNA end resection and homology-directed repair.

@article{Soria2013DifferentialCO,
  title={Differential contribution of HP1 proteins to DNA end resection and homology-directed repair.},
  author={Gast{\'o}n Soria and Genevi{\`e}ve Almouzni},
  journal={Cell cycle},
  year={2013},
  volume={12 3},
  pages={
          422-9
        }
}
Heterochromatin protein 1 paralogs (HP1α, β and γ in mammals) are not only central in heterochromatin organization, but have also been linked to transcriptional activation at euchromatic regions, maintenance of telomere stability and, most recently, to the DNA damage response (DDR). However, how HP1 proteins contribute to the DDR at a molecular level, and whether HP1 paralogs within the same organism, as well as their respective orthologs, have overlapping or unique roles in the DDR, remain to… CONTINUE READING
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The response to DNA damage in heterochromatin domains

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