Differential consequences of lateral and central fluid percussion brain injury on receptor coupling in rat hippocampus.

@article{Delahunty1995DifferentialCO,
  title={Differential consequences of lateral and central fluid percussion brain injury on receptor coupling in rat hippocampus.},
  author={Th{\'e}r{\`e}se M. Delahunty and Ji Jiang and Q Z Gong and Raiford T. Black and Bruce G. Lyeth},
  journal={Journal of neurotrauma},
  year={1995},
  volume={12 6},
  pages={1045-57}
}
We have identified alterations in the responses of muscarinic and metabotropic receptors in rat hippocampus that persist for at least 15 days after central fluid percussion injury. This study compares the effect of lateral fluid percussion and central fluid percussion on these responses. Moderate injury was obtained by displacement and deformation of the brain within the closed cranial cavity using a fluid percussion device positioned either centrally or laterally. Carbachol and (+/-)-1… CONTINUE READING