Differential chemokine gene expression in corneal transplant rejection.

  title={Differential chemokine gene expression in corneal transplant rejection.},
  author={Satoru Yamagami and Dai Miyazaki and Santa Jeremy Ono and Mohamad R. Dana},
  journal={Investigative ophthalmology & visual science},
  volume={40 12},
PURPOSE To evaluate the differential gene expression of chemokines after corneal transplantation and to determine the chemokines associated with allograft rejection. METHODS Orthotopic mouse corneal transplantation was performed in two fully mismatched-strain combinations using C57BL/6 (H-2b) and BALB/c (H-2d) mice as recipients and BALB/c and C57BL/6 mice as donors. Normal nonsurgical eyes served as negative control specimens and syngeneic transplants (isografts) as control specimens for the… CONTINUE READING


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