Differential changes of potassium currents in CA1 pyramidal neurons after transient forebrain ischemia.

@article{Chi2000DifferentialCO,
  title={Differential changes of potassium currents in CA1 pyramidal neurons after transient forebrain ischemia.},
  author={Xian Chi and Zao Cheng Xu},
  journal={Journal of neurophysiology},
  year={2000},
  volume={84 6},
  pages={2834-43}
}
CA1 pyramidal neurons are highly vulnerable to transient cerebral ischemia. In vivo studies have shown that the excitability of CA1 neurons progressively decreased following reperfusion. To reveal the mechanisms underlying the postischemic excitability change, total potassium current, transient potassium current, and delayed rectifier potassium current in CA1 neurons were studied in hippocampal slices prepared before ischemia and at different time points following reperfusion. Consistent with… CONTINUE READING