Differential cell division in human X chromosome mosaics

  title={Differential cell division in human X chromosome mosaics},
  author={Peter W. Barlow},
Fibroblasts were grown from skin explants of 3 human females who are sex chromosome mosaics. The 3 cultures had the following chromosome complements: 45,X/46,XX, 45,X/46,XXqi and 45,X/47,XXX. Using thymidine labelling and Colcemid accumulation of metaphases it was found that in all 3 mosaic cultures the 45,X cells had a faster cell cycle than the second cell population. The difference in cell cycle duration was attributed to the longer G1 phase in the cells with 2 or 3 X chromosomes. The 2… CONTINUE READING


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Sex chimaerism and germ cell distribution in a series of chimaeric mice.

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