Differential behavioural and neurochemical effects of para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine in the rat

  title={Differential behavioural and neurochemical effects of para-methoxyamphetamine and 3,4-methylenedioxymethamphetamine in the rat},
  author={L. Daws and R. Irvine and P. D. Callaghan and Natasha P. Toop and F. Bochner},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  • L. Daws, R. Irvine, +2 authors F. Bochner
  • Published 2000
  • Chemistry, Medicine
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • 1. This study was prompted by recent deaths that have occurred after recreational administration of the substituted amphetamine para-methoxyamphetamine (PMA). Because relatively little is known regarding its mechanism(s) of action, its effects on physiological, behavioural and neurochemical parameters were compared with the well known effects of 3,4-methylenedioxymethamphetamine (MDMA). 2. Equivalent doses of PMA (5-20 mg/kg) produced greater hypothermia than MDMA at an ambient temperature of… CONTINUE READING
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