Differential behavior of cytotoxic effector cells against HLA antigens in strong genetic linkage disequilibrium


Five sets of cytotoxic effector cells were generated, using haploidentical, first degree relatives in five different families, against the HLA-A3; B7 serological determinants combined with different DR antigens. When tested against a panel of cells bearing combinations of the HLA-A, -B and -DR antigens it was shown that the HLA-B7 antigen was as strong a… (More)
DOI: 10.1007/BF00364495


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