Differential augmentation of in vivo natural killer cytotoxicity in normal primates with recombinant human interleukin-1 and granulocyte-macrophage colony-stimulating factor.

Abstract

The effect of recombinant human interleukin-1 (IL-1) alpha, granulocyte-macrophage colony-stimulating factor (GM-CSF), and combined factor therapy (CFT) on Rhesus monkey peripheral blood natural killer (NK) activity in vivo was compared. During a 14-day treatment period, IL-1-treated animals demonstrated a 170% increase in NK activity against K562 target… (More)

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@article{Davis1990DifferentialAO, title={Differential augmentation of in vivo natural killer cytotoxicity in normal primates with recombinant human interleukin-1 and granulocyte-macrophage colony-stimulating factor.}, author={T. A. Davis and Ra{\'u}l Monroy and Rob Skelly and Robert E Donahue and Thomas J Macvittie}, journal={Clinical and experimental immunology}, year={1990}, volume={79 3}, pages={436-42} }