Differential association of postsynaptic signaling protein complexes in striatum and hippocampus.

@article{Baucum2013DifferentialAO,
  title={Differential association of postsynaptic signaling protein complexes in striatum and hippocampus.},
  author={Anthony J Baucum and Abigail M. Brown and Roger J Colbran},
  journal={Journal of neurochemistry},
  year={2013},
  volume={124 4},
  pages={490-501}
}
Distinct physiological stimuli are required for bidirectional synaptic plasticity in striatum and hippocampus, but differences in the underlying signaling mechanisms are poorly understood. We have begun to compare levels and interactions of key excitatory synaptic proteins in whole extracts and subcellular fractions isolated from micro-dissected striatum and hippocampus. Levels of multiple glutamate receptor subunits, calcium/calmodulin-dependent protein kinase II (CaMKII), a highly abundant… CONTINUE READING
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