Differential association of polymorphisms in the TNFalpha region with psoriatic arthritis but not psoriasis.

@article{Hoehler2002DifferentialAO,
  title={Differential association of polymorphisms in the TNFalpha region with psoriatic arthritis but not psoriasis.},
  author={Thomas Hoehler and Steffen Grossmann and Beate Stradmann-Bellinghausen and Wojciech Kaluza and Esther Reuss and Kurt de Vlam and E. Veys and Elisabeth Maerker-Hermann},
  journal={Annals of the rheumatic diseases},
  year={2002},
  volume={61 3},
  pages={213-8}
}
OBJECTIVE To investigate the potential association of tumour necrosis factor alpha (TNFalpha) microsatellite and promoter alleles with psoriatic arthritis (PsA). METHODS DNA from 89 white patients with PsA, 65 patients with psoriasis, and 99 healthy white controls was investigated for two TNFalpha promoter (-238 and -308) and three microsatellite polymorphisms (TNFa, c, and d). Patients had previously been studied by serology for HLA class I antigens and by sequence-specific polymerase chain… CONTINUE READING