Differential allograft gene expression in acute cellular rejection and recurrence of hepatitis C after liver transplantation.

@article{Sreekumar2002DifferentialAG,
  title={Differential allograft gene expression in acute cellular rejection and recurrence of hepatitis C after liver transplantation.},
  author={Raghavakaimal Sreekumar and Deborah L Rasmussen and Russell H. Wiesner and Michael R. Charlton},
  journal={Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society},
  year={2002},
  volume={8 9},
  pages={814-21}
}
Treatment of acute cellular rejection (ACR) is associated with increased viral load, more severe histologic recurrence, and diminished patient and graft survival after liver transplantation for hepatitis C virus (HCV). Recurrence of HCV may be difficult to distinguish histologically from ACR. Because the immunologic mechanisms of ACR and HCV recurrence are likely to differ, we hypothesized that ACR is associated with the expression of a specific subset of immune activation genes that may serve… CONTINUE READING

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