Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors


The basis for differences in activity-dependent trafficking of AMPA receptors (AMPARs) and NMDA receptors (NMDARs) remains unclear. Using single-molecule tracking, we found different lateral mobilities for AMPARs and NMDARs: changes in neuronal activity modified AMPAR but not NMDAR mobility, whereas protein kinase C activation modified both. Differences in… (More)
DOI: 10.1038/nn1270


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