Differential activations of PKC/PKA related to microvasculopathy in diabetic GK rats.


Microvasculopathy is the most serious and predictable threat to the health of diabetic patients, which often results in end-stage renal disease, blindness, and limb amputations. Up to the present, the underlying mechanisms have remained elusive. Here, it was found that the differential activations of PKC/PKA were involved in diabetic microvasculopathy in… (More)
DOI: 10.1152/ajpendo.00184.2011