Differential activation of pp60(c-src) and pp62(c-yes) in human colorectal carcinoma liver metastases.

@article{Han1996DifferentialAO,
  title={Differential activation of pp60(c-src) and pp62(c-yes) in human colorectal carcinoma liver metastases.},
  author={Noel M. Han and Steven A. Curley and Gary E. Gallick},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1996},
  volume={2 8},
  pages={
          1397-404
        }
}
pp60(c-src) and pp62(c-yes) are protein tyrosine kinases whose specific activities are increased in primary colorectal carcinomas. Activity of pp60(c-src) is further increased in colorectal liver metastases. This study was undertaken to compare pp60(c-src) and pp62(c-yes) expression and activity in human colorectal carcinoma liver metastases and to determine the potential prognostic significance of differences in activation of these two kinases. The pp60(c-src) and pp62(c-yes) tyrosine kinase… CONTINUE READING
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