Differential activation of mitogen-activated protein kinase pathways after traumatic brain injury in the rat hippocampus.

@article{Otani2002DifferentialAO,
  title={Differential activation of mitogen-activated protein kinase pathways after traumatic brain injury in the rat hippocampus.},
  author={N. Otani and Hiroshi Nawashiro and Shinji Fukui and Namiko Nomura and Akiko Yano and Takahito Miyazawa and Katsuji Shima},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2002},
  volume={22 3},
  pages={327-34}
}
Mitogen-activated protein kinases, which play a crucial role in signal transduction, are activated by phosphorylation in response to a variety of mitogenic signals. In the present study, the authors used Western blot analysis and immunohistochemistry to show that phosphorylated extracellular signal-regulated protein kinase (p-ERK) and c-Jun NH2-terminal kinase (p-JNK), but not p38 mitogen-activated protein kinase, significantly increased in both the neurons and astrocytes after traumatic brain… CONTINUE READING
19 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…