Differential activation of T cell cytokine production by the extracellular signal-regulated kinase (ERK) signaling pathway.

@article{Egerton1996DifferentialAO,
  title={Differential activation of T cell cytokine production by the extracellular signal-regulated kinase (ERK) signaling pathway.},
  author={Martyn Egerton and David R. FitzPatrick and Andrew D. Catling and Anne Kelso},
  journal={European journal of immunology},
  year={1996},
  volume={26 10},
  pages={2279-85}
}
Stimulation of T cells via the T cell receptor (TCR) activates a number of signaling pathways that are potentially involved in the elicitation of physiological responses, such as the production of cytokines. The extracellular signal-regulated kinases (ERK) are a group of molecules activated in response to TCR ligation, whose role in T cell cytokine production is controversial. In this study, we have asked whether ERK activation is coupled to the production of a number of T cell-derived… CONTINUE READING

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