Differential Surface Expression of ADAM10 and ADAM17 on Human T Lymphocytes and Tumor Cells

Abstract

A disintegrin and metalloproteases (ADAMs) have been implicated in many processes controlling organismic development and integrity. Important substrates of ADAM proteases include growth factors, cytokines and their receptors and adhesion proteins. The inducible but irreversible cleavage of their substrates alters cell-cell communication and signaling. The… (More)
DOI: 10.1371/journal.pone.0076853

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