Differential S-nitrosylation of proteins in Alzheimer's disease.

  title={Differential S-nitrosylation of proteins in Alzheimer's disease.},
  author={Saadia Zahid and Rizma Khan and Michael Oellerich and Nuzhat Ahmed and Abdul R Asif},
Numerous studies have provided evidence regarding the involvement of protein S-nitrosylation in the progression of Alzheimer's disease (AD) pathology and its implication in the formation and accumulation of misfolded protein aggregates. The identification of S-nitrosylated proteins can be a major step toward the understanding of mechanisms leading to neuronal degeneration. The present study targeted S-nitrosylated proteins in AD hippocampus, substantia nigra and cortex using the following work… CONTINUE READING