Differential Roles of Ventral and Dorsal Streams for Conceptual and Production-Related Components of Tool Use in Acute Stroke Patients.

@article{Martin2016DifferentialRO,
  title={Differential Roles of Ventral and Dorsal Streams for Conceptual and Production-Related Components of Tool Use in Acute Stroke Patients.},
  author={Markus Martin and Lena-A. Beume and Dorothee K{\"u}mmerer and Charlotte S. M. Schmidt and Tobias Bormann and Andrea Dressing and Vera M. Ludwig and Roza M. Umarova and Irina Mader and Michel Rijntjes and Christoph P. Kaller and Cornelius Weiller},
  journal={Cerebral cortex},
  year={2016},
  volume={26 9},
  pages={
          3754-71
        }
}
Impaired tool use despite preserved basic motor functions occurs after stroke in the context of apraxia, a cognitive motor disorder. To elucidate the neuroanatomical underpinnings of different tool use deficits, prospective behavioral assessments of 136 acute left-hemisphere stroke patients were combined with lesion delineation on magnetic resonance imaging (MRI) images for voxel-based lesion-symptom mapping. Deficits affecting both the selection of the appropriate recipient for a given tool… 

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References

SHOWING 1-10 OF 145 REFERENCES

Critical brain regions for tool-related and imitative actions: a componential analysis.

TLDR
Visual posture information and kinematic capacities are differentially critical to the three types of actions studied here: the kinematics aspect is particularly critical for imitation of meaningless movement, capacity for tool-action posture representations are particularly necessary for pantomimed gestures to the sight of tools, and both capacities inform imitation of tool-related movements.

The neural basis of tool use.

TLDR
The contribution of the parietal lobe to tool use concerns general principles of tool use rather than knowledge about the prototypical use of common tools and objects, and the comprehension of mechanical interactions of the tool with other tools, recipients or material rather than the selection of grip formation and manual movements.

Neural bases of imitation and pantomime in acute stroke patients: distinct streams for praxis.

TLDR
Results indicate that imitation mainly relies on the dorso-dorsal stream for visuo-motor conversion and on-line movement control, and pantomime additionally requires ventro- dorsal and ventral streams for access to stored action engrams and retrieval of tool-action relationships.

Apraxia and the parietal lobes

The Neural Correlates of Planning and Executing Actual Tool Use

TLDR
It is found that object manipulations with both right and left hand recruit a common network strongly lateralized to the left hemisphere especially during planning but also action execution, providing evidence for left-lateralized occipito-temporo-parieto-frontal network of everyday tool use, which may help to characterize specific deficits in patients suffering from apraxia.

The ventral fiber pathway for pantomime of object use

...