Differential Response to Anti-VEGF Regimens in Age-Related Macular Degeneration Patients with Early Persistent Retinal Fluid.

@article{Jaffe2016DifferentialRT,
  title={Differential Response to Anti-VEGF Regimens in Age-Related Macular Degeneration Patients with Early Persistent Retinal Fluid.},
  author={Glenn J. Jaffe and Peter K. Kaiser and Desmond Thompson and Andrea Wheeler Gibson and Namrata Saroj and Robert L Vitti and Alyson J. Berliner and Jeffrey S. Heier},
  journal={Ophthalmology},
  year={2016},
  volume={123 9},
  pages={1856-64}
}
PURPOSE To compare the effect of intravitreal aflibercept or ranibizumab drug type and frequency on visual acuity outcomes in eyes with neovascular age-related macular degeneration (NVAMD) and early persistent retinal fluid after 3 initial monthly injections. DESIGN A post hoc analysis of eyes enrolled in VIEW 1 and VIEW 2, 2 similarly designed, randomized, phase 3 trials. PARTICIPANTS A total of 1815 eyes with NVAMD from VIEW 1 and VIEW 2. METHODS Analyses included patients with known… CONTINUE READING

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