Differential Requirements of Two recA Mutants for Constitutive SOS Expression in Escherichia coli K-12

@article{Long2008DifferentialRO,
  title={Differential Requirements of Two recA Mutants for Constitutive SOS Expression in Escherichia coli K-12},
  author={Jarukit Edward Long and Nicholas Renzette and Richard C. Centore and Steven J. Sandler},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={1896 - 1899}
}
BACKGROUND Repairing DNA damage begins with its detection and is often followed by elicitation of a cellular response. In E. coli, RecA polymerizes on ssDNA produced after DNA damage and induces the SOS Response. The RecA-DNA filament is an allosteric effector of LexA auto-proteolysis. LexA is the repressor of the SOS Response. Not all RecA-DNA filaments… CONTINUE READING