Differential Regulation of Type I and Type III Interferon Signaling

@inproceedings{Stanifer2019DifferentialRO,
  title={Differential Regulation of Type I and Type III Interferon Signaling},
  author={Megan L. Stanifer and Kalliopi Pervolaraki and Steeve Boulant},
  booktitle={International journal of molecular sciences},
  year={2019}
}
Interferons (IFNs) are very powerful cytokines, which play a key role in combatting pathogen infections by controlling inflammation and immune response by directly inducing anti-pathogen molecular countermeasures. There are three classes of IFNs: type I, type II and type III. While type II IFN is specific for immune cells, type I and III IFNs are expressed by both immune and tissue specific cells. Unlike type I IFNs, type III IFNs have a unique tropism where their signaling and functions are… CONTINUE READING

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