Differential Regulation and Function of CD73, a Glycosyl-Phosphatidylinositol–linked 70-kD Adhesion Molecule, on Lymphocytes and Endothelial Cells

@article{Airas1997DifferentialRA,
  title={Differential Regulation and Function of CD73, a Glycosyl-Phosphatidylinositol–linked 70-kD Adhesion Molecule, on Lymphocytes and Endothelial Cells},
  author={Laura Airas and Jussi Niemel{\"a} and Marko Salmi and Tarja Puurunen and David J. Smith and Sirpa Jalkanen},
  journal={The Journal of Cell Biology},
  year={1997},
  volume={136},
  pages={421 - 431}
}
CD73, otherwise known as ecto-5'-nucleotidase, is a glycosyl-phosphatidylinositol-linked 70-kD molecule expressed on different cell types, including vascular endothelial cells (EC) and certain subtypes of lymphocytes. There is strong evidence for lymphocyte CD73 having a role in several immunological phenomena such as lymphocyte activation, proliferation, and adhesion to endothelium, but the physiological role of CD73 in other cell types is less clear. To compare the biological characteristics… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 61 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol–anchored lymphocyte differentiation antigen ecto-59-nucleotidase (CD73)

  • L. F. Thompson, J. M. Ruedi, +6 authors A. H. Lucas
  • Tissue Antigens
  • 1990
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…