Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients

@inproceedings{Jin2012DifferentialPP,
  title={Differential Proteome Profiling Using iTRAQ in Microalbuminuric and Normoalbuminuric Type 2 Diabetic Patients},
  author={Jonghwa Jin and Yun Hyi Ku and Yikwon Kim and Yeonjung Kim and Kyunggon Kim and Ji Yoon Lee and Young Min Cho and Hong Kyu Lee and Kyong Soo Park and Youngsoo Kim},
  booktitle={Experimental diabetes research},
  year={2012}
}
Diabetic nephropathy (DN) is a long-term complication of diabetes mellitus that leads to end-stage renal disease. Microalbuminuria is used for the early detection of diabetic renal damage, but such levels do not reflect the state of incipient DN precisely in type 2 diabetic patients because microalbuminuria develops in other diseases, necessitating more accurate biomarkers that detect incipient DN. Isobaric tags for relative and absolute quantification (iTRAQ) were used to identify urinary… CONTINUE READING

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