Differential N-Glycosylation Patterns in Lung Adenocarcinoma Tissue.

  title={Differential N-Glycosylation Patterns in Lung Adenocarcinoma Tissue.},
  author={L. Renee Ruhaak and Sandra L. Taylor and Carol D Stroble and Uyen Thao Nguyen and Evan Parker and Ting Song and Carlito B. Lebrilla and William Rom and Harvey I. Pass and Kyoungmi Kim and Karen Kelly and Suzanne Miyamoto},
  journal={Journal of proteome research},
  volume={14 11},
To decrease the mortality of lung cancer, better screening and diagnostic tools as well as treatment options are needed. Protein glycosylation is one of the major post-translational modifications that is altered in cancer, but it is not exactly clear which glycan structures are affected. A better understanding of the glycan structures that are differentially regulated in lung tumor tissue is highly desirable and will allow us to gain greater insight into the underlying biological mechanisms of… CONTINUE READING
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