Differential Inflammatory Response to Inhaled Lipopolysaccharide Targeted Either to the Airways or the Alveoli in Man

@inproceedings{Moeller2012DifferentialIR,
  title={Differential Inflammatory Response to Inhaled Lipopolysaccharide Targeted Either to the Airways or the Alveoli in Man},
  author={Winfried Moeller and Irene Heimbeck and Thomas P. J. Hofer and G{\"u}lnaz Khadem Saba and Margot Neiswirth and Marion Frankenberger and Loems Ziegler-Heitbrock},
  booktitle={PloS one},
  year={2012}
}
Endotoxin (Lipopolysaccharide, LPS) is a potent inducer of inflammation and there is various LPS contamination in the environment, being a trigger of lung diseases and exacerbation. The objective of this study was to assess the time course of inflammation and the sensitivities of the airways and alveoli to targeted LPS inhalation in order to understand the role of LPS challenge in airway disease.In healthy volunteers without any bronchial hyperresponsiveness we targeted sequentially 1, 5 and 20… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 59 references

C-reactive protein, inflammation, and innate immunity.

Immunologic research • 2001
View 10 Excerpts
Highly Influenced

Exacerbations of asthma and COPD: definitions, clinical manifestations and epidemiology.

Contributions to microbiology • 2007
View 8 Excerpts
Highly Influenced

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