Differential Gene Expression Profile Associated with the Abnormality of Bone Marrow Mesenchymal Stem Cells in Aplastic Anemia

@inproceedings{Li2012DifferentialGE,
  title={Differential Gene Expression Profile Associated with the Abnormality of Bone Marrow Mesenchymal Stem Cells in Aplastic Anemia},
  author={Jianping Li and Shaoguang Yang and Shihong Lu and Hui Zhao and Jianming Feng and Wenqian Li and Fengxia Ma and Qian Ren and Bin Liu and Lei Zhang and Yizhou Zheng and Zhong Han},
  booktitle={PloS one},
  year={2012}
}
Aplastic anemia (AA) is generally considered as an immune-mediated bone marrow failure syndrome with defective hematopoietic stem cells (HSCs) and marrow microenvironment. Previous studies have demonstrated the defective HSCs and aberrant T cellular-immunity in AA using a microarray approach. However, little is known about the overall specialty of bone marrow mesenchymal stem cells (BM-MSCs). In the present study, we comprehensively compared the biological features and gene expression profile… CONTINUE READING
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