Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress

@article{Huo2017DifferentialEO,
  title={Differential Expression of miRNAs in the Respiratory Tree of the Sea Cucumber Apostichopus japonicus Under Hypoxia Stress},
  author={D. Huo and Lina Sun and Xiaoni Li and Xiaoshang Ru and S. Liu and Libin Zhang and Lili Xing and Hongsheng Yang},
  journal={G3: Genes|Genomes|Genetics},
  year={2017},
  volume={7},
  pages={3681 - 3692}
}
The sea cucumber, an important economic species, has encountered high mortality since 2013 in northern China because of seasonal environmental stress such as hypoxia, high temperature, and low salinity. MicroRNAs (miRNAs) are important in regulating gene expression in marine organisms in response to environmental change. In this study, high-throughput sequencing was used to investigate alterations in miRNA expression in the sea cucumber under different levels of dissolved oxygen (DO). Nine… Expand
Understanding microRNAs regulation in heat shock response in the sea cucumber Apostichopus japonicus
TLDR
This study determined the expression profiles of miRNAs under heat stress (HS) in A. japonicus by using high‐throughput sequencing technique and identified 17 key miRNA‐target pairs potentially regulated HSR of sea cucumbers. Expand
Salinity stress-induced differentially expressed miRNAs and target genes in sea cucumbers Apostichopus japonicus
TLDR
It is suggested that sea cucumbers deal with salinity stress via changes in amino acid metabolism, ion channels, transporters, and aquaporins, under stimulation by environmental signals, and that this process requires energy from carbohydrate and fatty acid metabolism. Expand
Sea cucumbers in a high temperature and low dissolved oxygen world: Roles of miRNAs in the regulation of environmental stresses.
TLDR
Key DE-miRNAs with potentially targeted genes associated with heat shock and hypoxia response were determined and may help explaining the role of miRNA regulation in stress resistance, as well as the potential molecular regulation mechanism of the echinoderm A. japonicus in the context of global warming. Expand
Potential role for microRNA in facilitating physiological adaptation to hypoxia in the Pacific whiteleg shrimp Litopenaeus vannamei.
TLDR
This study revealed that the differentially expressed miRNAs may regulate host response to Hypoxia by modulating the expression of stress response genes such as HIF1a and p53 and affecting key cellular events involved in hypoxia adaptation. Expand
Metabolome responses of the sea cucumber Apostichopus japonicus to multiple environmental stresses: Heat and hypoxia.
TLDR
Combined environmental stressors have a more extensive impact on the metabolites of the respiratory tree in sea cucumbers than single stress, which would facilitate further development of the sea cucumber as an echinoderm model to study mechanisms of response to adverse environments, and help advance knowledge of the adaptation of marine organisms to global climate change. Expand
The regulation mechanism of lncRNAs and mRNAs in sea cucumbers under global climate changes: Defense against thermal and hypoxic stresses
TLDR
More comprehensive responses were elicited by the combined thermal/hypoxic stress treatment than by individual stresses alone in sea cucumbers, laying the groundwork for future research on molecular mechanisms of echinoderm responses to thermal and hypoxic stress in the context of global climate changes. Expand
Impact of hypoxia stress on the physiological responses of sea cucumber Apostichopus japonicus: respiration, digestion, immunity and oxidative damage
TLDR
The physiological responses of Apostichopus japonicus to oxygen deficiency was illustrated, including induced oxidative response and immune defense and changed digestive enzymes activities, which could help to develop a better understanding of the responsive mechanism of sea cucumber under hypoxia stress. Expand
Metabolic response of longitudinal muscles to acute hypoxia in sea cucumber Apostichopus japonicus (Selenka): A metabolome integrated analysis.
TLDR
Results suggested that fatty acid synthesis was strengthened significantly in both treatment groups, and the degree was higher in EG24 than in EG6, providing valuable information towards understanding the special adaptive mechanism of A. japonicus to hypoxia stress. Expand
Identification of molecular markers for superior quantitative traits in a novel sea cucumber strain by comparative microRNA-mRNA expression profiling.
TLDR
"Anyuan No. 1" is suitable for large-scale cultivation extension due to its better adaptability to the South China Sea area and "miR10-ACADL" is identified as a potential module for further molecular marker-assisted selective breeding of A. japonicus. Expand
Heat and Hypoxia Exposure Mediates Circadian Rhythms Response via Methylation Modification in Apostichopus japonicas
  • Jiong Wu, Weiwei Zhang, Chenghua Li
  • Frontiers in Marine Science
  • 2021
As global warming progresses, heat and hypoxia are gradually becoming important factors threatening the survival, reproduction, and development of marine organisms. To determine the effect of heatExpand
...
1
2
...

References

SHOWING 1-10 OF 77 REFERENCES
High-Throughput Sequencing Reveals Differential Expression of miRNAs in Intestine from Sea Cucumber during Aestivation
The regulatory role of miRNA in gene expression is an emerging hot new topic in the control of hypometabolism. Sea cucumber aestivation is a complicated physiological process that includes obviousExpand
The Roles of Two miRNAs in Regulating the Immune Response of Sea Cucumber
TLDR
It is found that miR-137 expression was slightly attenuated andMiR-2008 was significantly enhanced after Vibrio splendidus infection or Lipopolysaccharides application, and small interfering RNA mediated AjBHMT knockdown and Hcy exposure analyses both significantly increased reactive oxygen species (ROS) production and decreased the number of surviving invasive pathogen in sea cucumber coelomocytes. Expand
MicroRNA Regulation in Extreme Environments: Differential Expression of MicroRNAs in the Intertidal Snail Littorina littorea During Extended Periods of Freezing and Anoxia
Several recent studies of vertebrate adaptation to environmental stress have suggested roles for microRNAs (miRNAs) in regulating global suppression of protein synthesis and/or restructuring proteinExpand
Identification and Characterization of MicroRNAs from Longitudinal Muscle and Respiratory Tree in Sea Cucumber (Apostichopus japonicus) Using High-Throughput Sequencing
TLDR
This study identified and characterized miRNAs in the LTM and RPT of sea cucumber (Apostichopus japonicus) using Illumina HiSeq 2000 platform and identified a set of 58 mi RNAs to be differentially expressed between LTMand RPT. Expand
Understanding regulation of microRNAs on intestine regeneration in the sea cucumber Apostichopus japonicus using high-throughput sequencing.
TLDR
High-throughput sequencing applied to investigate alterations of miRNA expression in regenerative intestine compared to normal intestine suggested that these miRNAs play important roles in specific cellular events (cell proliferation, migration, and apoptosis), metabolic regulation, and energy redistribution. Expand
Identification and comparative analysis of the oriental river prawn (Macrobrachium nipponense) microRNA expression profile during hypoxia using a deep sequencing approach.
TLDR
This study provides the first large-scale identification and characterization of M. nipponense miRNAs and their potential targets, and represents a foundation for further characterization of their roles in the regulation of the diversity of hypoxia processes. Expand
Integrated analysis of mRNA-seq and miRNA-seq in the liver of Pelteobagrus vachelli in response to hypoxia
TLDR
This study uses next-generation sequencing technology to characterise mRNA-seq and miRNA-seq of control- and hypoxia-treated P. vachelli livers and offers a deeper insight into the molecular mechanisms of Hypoxia adaptation. Expand
Large scale gene expression profiling during intestine and body wall regeneration in the sea cucumber Apostichopus japonicus.
TLDR
Fourteen new candidate gene sequences, discovered for the first time in this study, will greatly enable future research - using the sea cucumber model - into the molecular mechanisms associated with intestine and body wall regeneration. Expand
Identification and Expression Profiling of MicroRNAs in the Brain, Liver and Gonads of Marine Medaka (Oryzias melastigma) and in Response to Hypoxia
TLDR
This is the first study to identify miRNAs in O. melastigma using small RNA deep sequencing technology and suggested that 55 miRNA types from 34 families are common to all tested tissues, while some of the mi RNAs are tissue-en enriched or sex-enriched. Expand
Transcriptome Sequencing and Characterization for the Sea Cucumber Apostichopus japonicus (Selenka, 1867)
TLDR
Pyrosequencing was proven to be efficient in rapidly identifying a large set of genes for the sea cucumber A. japonicus and identified candidate aestivation-related genes. Expand
...
1
2
3
4
5
...