Differential Expression of PRAMEL1, a Cancer/Testis Antigen, during Spermatogenesis in the Mouse

@inproceedings{Mistry2013DifferentialEO,
  title={Differential Expression of PRAMEL1, a Cancer/Testis Antigen, during Spermatogenesis in the Mouse},
  author={Bhavesh V. Mistry and Yaqi Zhao and Ti-Cheng Chang and Hiroshi Yasue and Mitsuru Chiba and Jon M. Oatley and Francisco Javier Hern{\'a}ndez D{\'i}az and W Liu},
  booktitle={PloS one},
  year={2013}
}
PRAME belongs to a group of cancer/testis antigens (CTAs) that are characterized by their restricted expression in normal gametogenic tissues and a variety of tumors. The PRAME family is one of the most amplified gene families in the mouse and other mammalian genomes. Members of the PRAME gene family encode leucine-rich repeat (LRR) proteins functioning as transcription regulators in cancer cells. However, the role of PRAME in normal gonads is unknown. The objective of this study is to… CONTINUE READING
3 Citations
54 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Sperry AO (2011) PP1 forms an active complex with TLRR (lrrc67), a putative PP1 regulatory subunit, during the early stages of spermiogenesis in mice

  • R Wang
  • PLoS ONE
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…