Differential Expression of Genes and DNA Methylation associated with Prenatal Protein Undernutrition by Albumen Removal in an avian model.

@article{Willems2016DifferentialEO,
  title={Differential Expression of Genes and DNA Methylation associated with Prenatal Protein Undernutrition by Albumen Removal in an avian model.},
  author={Els Willems and Carlos Guerrero-Bosagna and Eddy M-P Decuypere and Steven B Janssens and Johan Buyse and Nadine Buys and P. V. Jensen and Nadia Everaert},
  journal={Scientific reports},
  year={2016},
  volume={6},
  pages={20837}
}
Previously, long-term effects on body weight and reproductive performance have been demonstrated in the chicken model of prenatal protein undernutrition by albumen removal. Introduction of such persistent alterations in phenotype suggests stable changes in gene expression. Therefore, a genome-wide screening of the hepatic transcriptome by RNA-Seq was performed in adult hens. The albumen-deprived hens were created by partial removal of the albumen from eggs and replacement with saline early… CONTINUE READING
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