Differential Effects of ET-1, ET-2, and ET-3 on Pancreatic Microcirculation, Tissue Integrity, and Inflammation

Abstract

The differential effects of endothelin-1, -2, and -3 (ET-1, ET-2, and ET-3) on pancreatic microcirculation, pancreatic tissue integrity, and an initial inflammatory response, which are three distinct characteristics of acute necrotizing pancreatitis, were investigated in a dose-dependent manner in rats using in vivo microscopy. Red blood cell (RBC) velocity… (More)
DOI: 10.1023/A:1010640002323

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