Differential Effect of w3 PUFA Supplementations on Na,K-ATPase and Mg-ATPase Activities: Possible Role of the Membrane w6/w3 Ratio

@article{DjemliShipkolye2003DifferentialEO,
  title={Differential Effect of w3 PUFA Supplementations on Na,K-ATPase and Mg-ATPase Activities: Possible Role of the Membrane w6/w3 Ratio},
  author={A. Djemli-Shipkolye and D Raccah and G{\'e}rard Pi{\'e}roni and Ph. Vague and Thierry Charles Coste and Alain Gerbi},
  journal={The Journal of Membrane Biology},
  year={2003},
  volume={191},
  pages={37-47}
}
Several functional properties of Na,K-ATPase are strongly dependent on membrane fatty acid composition, but the underlying mechanism is still not well defined. We have studied the effects of two types of supplementations enriched in the w3 polyunsaturated fatty acids on the Na,K-ATPase and Mg-ATPase activities in sciatic nerve (SN) and red blood cells (RBC). Eight groups of rats, controls and diabetics, received a standard diet, supplemented or not with 30 or 60 mg/kg/day of docosahexaenoic… CONTINUE READING