Differential Association of Tau With Subsets of Microtubules Containing Posttranslationally-Modified Tubulin Variants in Neuroblastoma Cells

@article{Saragoni2000DifferentialAO,
  title={Differential Association of Tau With Subsets of Microtubules Containing Posttranslationally-Modified Tubulin Variants in Neuroblastoma Cells},
  author={Lorena Saragoni and Paula Andrea Velilla Hern{\'a}ndez and Ricardo B. Maccioni},
  journal={Neurochemical Research},
  year={2000},
  volume={25},
  pages={59-70}
}
Neuronal cells display different subsets of dynamic microtubules. In axons and extending neurites, this intrinsic dynamics is modulated by the microtubule-associated protein tau. Moreover, posttranslational modifications of tubulin, namely acetylation, tyrosination or glutamylation are directly involved in determining the stability of neuronal microtubules. Studies were carried out to analyze the interaction patterns of tau with subsets of microtubules in N2A neuroblastoma cells, which can… CONTINUE READING

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