Differential (18)F-FDG and (18)F-FLT Uptake on Serial PET/CT Imaging Before and During Definitive Chemoradiation for Non-Small Cell Lung Cancer.

@article{Everitt2014DifferentialA,
  title={Differential (18)F-FDG and (18)F-FLT Uptake on Serial PET/CT Imaging Before and During Definitive Chemoradiation for Non-Small Cell Lung Cancer.},
  author={Sarah Everitt and David Ball and Rodney J Hicks and Jason W Callahan and Nikki M Plumridge and Marnie Ellen Collins and Alan Herschtal and David S. Binns and Tomas Kron and Michal Schneider and Michael P Macmanus},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2014},
  volume={55 7},
  pages={
          1069-74
        }
}
UNLABELLED We aimed to prospectively observe cellular metabolism and proliferation in patients with non-small-cell lung cancer (NSCLC) during radical chemoradiation therapy using serial PET/CT with (18)F-FDG and 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT). METHODS Twenty patients with stage I-III NSCLC and candidates for radical chemoradiation therapy (60 Gy in 30 fractions over 6 wk) were recruited. (18)F-FDG and (18)F-FLT PET/CT were performed at baseline and during therapy (weeks 2 and 4… CONTINUE READING
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