Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors.

@article{Leberbauer2005DifferentSC,
  title={Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors.},
  author={Cornelia Leberbauer and Florence Boulm{\'e} and Gertrud Unfried and Johannes Huber and Hartmut Beug and Ernst W. M{\"u}llner},
  journal={Blood},
  year={2005},
  volume={105 1},
  pages={85-94}
}
Outgrowth, long-term self-renewal, and terminal maturation of human erythroid progenitors derived from umbilical cord blood in serum-free medium can be modulated by steroid hormones. Homogeneous erythroid cultures, as characterized by flow cytometry and dependence on a specific mixture of physiologic proliferation factors, were obtained within 8 days from a starting population of mature and immature mononuclear cells. Due to previous results in mouse and chicken erythroblasts, the proliferation… CONTINUE READING

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Normal erythroid progenitor renewal: essential players and functions revealed by cells from genetically modified mice

EM Deiner, H Dolznig, A Kolbus
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